Hydroxyethyl starch-containing polypeptide compositions
AssigneesWyeth, The Regent of the University of Colorado
InventorsNicholas Warne, Rebecca Koval, John Carpenter, Theodore Randolph, Suchart Chongpraset
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Abstract
The invention provides compositions containing hydroxyethyl starch and polypeptides, including therapeutic polypeptides such as interleukin-11, that provide for enhanced stability of the polypeptide following storage at room temperature or elevated temperatures.
Claims18
A composition comprising a polypeptide, a disaccharide and a hydroxyethyl starch wherein said composition has a glass transition temperature of at least 60° C.
13-36. (canceled)
A method of increasing platelet production in a subject, the method comprising administering a subject in need thereof a composition comprising a polypeptide, a disaccharide, and hydroxyethyl starch.
Dependencies are inferred from the claim text.