Identification of Porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsAnn Progulske-Fox, Jeffrey Hillman, Martin Handfield
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Abstract
The invention provides compositions and methods for the detection of Porphyromonas gingivalis and for the treatment and prevention of diseases and infections caused by P. gingivalis.
Claims32
An isolated immunogenic polypeptide comprising at least about 5 contiguous amino acids of an amino acid sequence selected from the group consisting of SEQ ID NOs:167-226, 228-261, and 263-354.
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:167-226, 228-261, and 263-354.
An isolated polynucleotide comprising at least about 15 contiguous nucleic acids of a sequence selected from the group consisting of SEQ ID NOs:1-166, 227, and 262 and degenerate variants thereof.
An isolated polynucleotide comprising a sequence shown in SEQ ID NOs:1-166, 227, and 262 and degenerate variants thereof.
Dependencies are inferred from the claim text.