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AssigneeLaboratoires Carilene
InventorStephane Desjonqueres
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The invention relates to an oily pharmaceutical composition based on peroxidised lipids and on silica, characterised in that it contains, as essential constituents, peroxidised lipids which have a degree of peroxidation of between 5 and 600 milli-equivalents per kilogram, and silica which is dispersed within said peroxidised lipids at a concentration of greater than or equal to 0.5% by weight and less than 4% by weight with respect to the weight of said composition. In this composition, the peroxidised lipids are preferably obtained by peroxidation of a natural plant oil and the silica is preferably colloidal silica. The invention also relates to the use of the composition for the preparation of a pharmaceutical composition which is intended for treating xerostomia.
An oily pharmaceutical composition based on peroxidised lipids and on silica, characterised in that it contains, as essential constituents, peroxidised lipids which have a degree of peroxidation of between 5 and 600 milli-equivalents per kilogram, and silica which is dispersed within said peroxidised lipids at a concentration by weight of greater than or equal to 0.5% and less than 4%.
The pharmaceutical composition according to claim 14, characterised in that the natural oil is selected from the group consisting of sweet almond oil, hazelnut oil, groundnut oil, maize oil, grapeseed oil, sesame oil, and safflower oil, and their mixtures.
12-13. (canceled)
A method for treatment of xerostomia, comprising the application by spraying in the mouth a composition comprising peroxidised lipids which have a degree of peroxidation of between 5 and 600 milli-equivalents per kilogram, said composition having a viscosity adapted for lining the buccal cavity and tongue.
A method according to claim 26, wherein the composition contains 0.5 to 3.5% by weight of silica.
A method according to claim 26, wherein the silica is in a form of colloidal silica.
Dependencies are inferred from the claim text.