Device for transdermal administration of drugs including acrylic polymers
AssigneeNoven Pharmaceuticals, Inc.
InventorDavid Kanios
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Abstract
A transdermal delivery system is provided where the drug delivery rates, onset and profiles of at least one active agent are controlled by selectively manipulating the monomeric make up of an acrylic-based polymer in the transdermal drug delivery system. The drug carrier composition may be comprised of (a) one or more acrylic-based polymers having one or more different monomers selected from the group consisting of hard and soft monomers; (b) one or more silicone-based polymers; and (c) one or more active agents where the device provides a desired solubility for the active agent and controls drug delivery rates, onset and profiles of at least one active agent.
Claims19
A transdermal drug delivery system comprising a blend of:
- (a) a polymer composition of at least one acrylic-based polymer which acrylic-based polymer is polymerized with monomers that include:
- (i) a soft acrylic monomer having a glass transition temperature (Tg) from about −70° C. to about −10° C. in an amount of from about 20 to about 70% by weight of the acrylic-based polymer;
- and (ii) a hard acrylic monomer having a glass transition temperature (Tg) from about −5° C. to about 120° C. in an amount of from about 30 to about 80% by weight of the acrylic-based polymer;
- and
- (b) 0.1% to about 50% by weight of the transdermal drug delivery system of one or more drugs incorporated into the polymer composition.
Dependencies are inferred from the claim text.