1,4,7,10-Tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them
OwnerJohannes Platzek, Heinz Gries +3inventors
InventorsJohannes Platzek, Heinz Gries, Hanns-Joachim Weinmann, Gabriele Schuhmann-Giampieri, Wolf-Rudiger Press
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Abstract
1,4,7,10-Tetraazacyclodedecane butyltriols of general formula IA in which R1 means hydrogen or a metal ion equivalent independent of one another and R2 means a butyltriol radical as well as their salts with organic or inorganic bases or amino acids are valuable pharmaceutical agents.
Claims3
1-19. (canceled)
A method of performing in vivo NMR spectroscopy in a patient comprising administering a compound as a susceptibility agent which has the formula IA
- in which
- each R1 is hydrogen or a metal ion equivalent, independent of one another and
- R2 is butyltriol
- or a salt thereof with an organic or inorganic base or an amino acid, and at least two of the substitutens R1 are metal ion equivalents.
A method of radiation therapy of a patient comprising administering as a photon and electron emitting agent, a compound which has the formula IA
- in which
- each R1 is hydrogen or a metal ion equivalent, independent of one another and
- R2 is butyltriol
- or a salt thereof with an organic or inorganic base or an amino acid, and at least two of the substitutens R1 are metal ion equivalents.
Dependencies are inferred from the claim text.