Electrophoresis apparatus
OwnerRyoji Inaba, Motohiro Yamazaki +5inventors
InventorsRyoji Inaba, Motohiro Yamazaki, Akihiro Suzuki, Miho Ozawa, Daizo Tokinaga, Tomonari Morioka, Seiichi Ugai
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Abstract
In an electrophoresis apparatus comprising capillaries for containing therein fluorescence-labeled substances, and a sensor for irradiating the capillaries with exciting light and detecting fluorescences, the sensor has a substrate including a datum surface for holding thereon the capillaries, and a groove sinking from the datum surface, and the groove has a plurality of reflecting surfaces for reflecting thereon the fluorescences emitted from the capillaries by a plurality of times.
Claims18
An electrophoresis apparatus comprising capillaries for containing therein fluorescence-labeled substances, and a sensor for irradiating the capillaries with exciting light and detecting fluorescences,
- wherein the sensor has a substrate including a datum surface for holding thereon the capillaries, and a groove sinking from the datum surface, and the groove has a plurality of reflecting surfaces for reflecting thereon the fluorescences emitted from the capillaries by a plurality of times.
An electrophoresis apparatus comprising capillaries for containing therein fluorescence-labeled substances, and a sensor for irradiating the capillaries with exciting light and detecting fluorescences,
- wherein the capillaries are arranged on the substrate and in an optically transmissive medium other than the atmosphere in the sensor, and the substrate is formed of a transparent material whose refractive index is substantially equal to a refractive index of the optically transmissive medium.
An electrophoresis apparatus for detecting a substance with marking by fluorochrome by detecting a fluorescence emitted by the fluorochrome in a specimen, comprising,
- capillaries each of which is capable of passing therein the substance,
- a light source for irradiating the capillaries with a light so that the fluorochrome generates the fluorescence,
- a sensor for detecting the fluorescence emitted from each of the capillaries, and
- a substrate having a base planar surface along which parts of the capillaries are capable of being arranged to hold the other parts of the capillaries so that the other parts of the capillaries are capable of being irradiated with the light,
- wherein the substrate has a fluorescence receiving surface arranged to receive thereon the fluorescences emitted from the other parts of the capillaries, prevented from extending perpendicular to the base planar surface, and prevented from extending parallel to the base planar surface.
An electrophoresis apparatus for detecting a substance with marking by fluorochrome by detecting a fluorescence emitted by the fluorochrome in a specimen, comprising,
- capillaries each of which is capable of passing therein the substance,
- a light source for irradiating the capillaries with a light so that the fluorochrome generates the fluorescence,
- a sensor for detecting the fluorescence emitted from each of the capillaries, and
- a substrate having a base planar surface along which parts of the capillaries are capable of being arranged to hold the other parts of the capillaries so that the other parts of the capillaries are capable of being irradiated with the light,
- wherein an optically transmissive medium other than the atmosphere is capable of being received between the fluorescence receiving surface and the other parts of the capillaries, and
- a difference in refractive index between a material forming the fluorescence receiving surface and the optically transmissive medium is smaller than a difference in refractive index between a material forming the fluorescence receiving surface and the atmosphere.
Dependencies are inferred from the claim text.