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US 2006/0069349 A1Published application
Method and device for delivering substance to tissue layers
OwnerRobert Ganz, Brian Zelickson +1inventors
InventorsRobert Ganz, Brian Zelickson, Mark Rydell
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Abstract
A method and apparatus is described that includes a catheter and a penetrating member at a distal end of the catheter for penetrating a tissue. The penetrating member can have a lumen in communication with the catheter, the lumen having an opening at a surface of the penetrating member to deliver a substance through the lumen. The device includes means for determining a location of the opening relative to the tissue.
Claims56
An apparatus comprising:
- an endoscope;
- a flexible catheter adapted to be inserted via the endoscope to deliver a substance to a tissue from an internal aspect;
- a penetrating member at a distal end of the catheter for penetrating the tissue, the penetrating member having a lumen in communication with the catheter, the lumen having an opening at a surface of the penetrating member to deliver the substance through the lumen;
- and
- means for determining a location of the opening relative to the tissue.
2 more elements
An apparatus comprising:
- a catheter having a first lumen for delivering a substance through the first lumen and having a second lumen for passing a fluid through the catheter;
- and a member to monitor a flow-rate of the fluid through the second lumen, wherein the flow-rate of the fluid through the second lumen is used to determine a location of a distal opening of the first lumen relative to the tissue.
A method comprising:
- inserting a catheter into a body;
- delivering a fluid through the catheter and monitoring a flow rate of the fluid out of an opening of the catheter;
- inserting the catheter into a tissue;
- and
- injecting a therapeutic material into the tissue through the catheter when it is determined that the flow rate is reduced, indicating that the opening of the catheter is located within the tissue.
2 more elements
A method comprising:
- inserting a catheter into a body;
- delivering a fluid through a first lumen of the catheter;
- monitoring a flow rate of the fluid or a pressure of the fluid within the first lumen;
- inserting the catheter into a tissue;
- and
- delivering a substance through the catheter when it is determined, by monitoring the flow rate or the pressure, that the catheter is properly located.
3 more elements
A method comprising:
- inserting a catheter into a body, the catheter having a penetrating member on a distal end of the catheter;
- inserting a tip of the penetrating member into a tissue;
- monitoring a pressure proximate the tip;
- and
- delivering a substance through the penetrating member when the pressure indicates that the tip is properly located for the substance.
2 more elements
Dependencies are inferred from the claim text.