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OwnerNorikazu Tabata, Kazuhiro Tanahashi +1inventors
InventorsNorikazu Tabata, Kazuhiro Tanahashi, Megumi Nakanishi
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This invention provides an embolization material used for blocking a blood vessel in vivo for stopping the blood flow. The most suitable embolization material has a water swelling ratio of 30% or more, is degradable in a phosphate buffered saline, is formed as virtually spherical particles, and is preferably composed of a water insoluble poly(ethylene glycol) copolymer, wherein when the film formed from said polymer is saturated with water, it has an elastic modulus in tension of 1500 MPa or less. The embolization material of this invention can reliably block a blood vessel at an intended site without causing cohesion or clogging in a catheter or in the blood vessel at other than the intended site. Thereafter, the blocked site concerned can be liberated from the embolized state by degradation, and the degraded components can be metabolized or excreted outside the body.
An embolization material that has a water swelling ratio of 30% or more and is formed as particles containing a synthetic polymer, being degradable in a phosphate buffered saline of 37° C.
An embolization material that has a water swelling ratio of 30% or more and is degradable in a phosphate buffered saline of 37° C., being formed as virtually spherical particles with an average particle size of 50 μm or more.
An embolization material that is composed of a water insoluble polymer, in which when the film formed from the water insoluble polymer is saturated with water, it has an elastic modulus in tension of 1500 MPa or less.
An embolization material comprising a water insoluble poly(ethylene glycol) copolymer.
An embolization material, that contains a synthetic polymer, has a water swelling ratio of 30% or more, is degradable in a phosphate buffered saline of 37° C., and is formed as virtually spherical particles with an average particle size of 50 micrometer or more, wherein the synthetic polymer is a water insoluble poly(ethylene glycol) copolymer and the film formed from the synthetic polymer and saturated with water has an elastic modulus in tension of 1500 MPa or less.
Dependencies are inferred from the claim text.