Back to results
US 2006/0069131 A1Published application
Novel complexes of fatty acid esters of polyhydroxyalkanes and pyridine carboxy derivatives
AssigneeAstion Dermatology A/S
InventorMorten Weidner
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel combinations of fatty acid derivatives and pyridine carboxy derivatives, including fatty acid esters with glycerol and 3-carboxy pyridine derivatives such as niacinamide. Such combinations have surprisingly shown antiviral and anti-microbial activity and the use for the treatment of inflammatory conditions and infections is disclosed herein.
Claims31
1-62. (canceled)
A composition comprising a chemical complex comprising a combination of:
- i) a fatty acid ester in the form of a mono-ester or in the form of a di-ester of formula I or isomers thereof,
- wherein n is 3;
- each R1 and R2 is independently selected from the group consisting of H, OH, OM, OR′, O—CO—R′, straight-chain or branched C1-C6 alkyl and straight-chain or branched C2-C6 alkenyl, provided that one or two of R1 and R2 is —O—CO—R′ and at least one of R1 and R2 is OH;
- R′ is selected from the group consisting of C6-C14 alkyl and C6-C20 alkenyl, and M is an alkali metal;
- and
- ii) niacinamide, a salt or a derivative thereof, wherein the derivative is selected from the group consisting of niacinamide derivatives with one substitution of the ring with substituents selected from halogen, NH2, methyl, OR and SH and from niacinamide derivatives wherein the amide group is in the form of its secondary amide or its tertiary amide.
3 more elements
Dependencies are inferred from the claim text.