Chemokine receptor binding heterocyclic compounds
OwnerGary Bridger, Eva Boehringer +3inventors
InventorsGary Bridger, Eva Boehringer, Dominique Schols, Renato Skerlj, David Bogucki
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Abstract
The present invention is drawn to novel antiviral compounds, pharmaceutical compositions and their use. More specifically this invention is drawn to derivatives of monocyclic polyamines which have activity in standard tests against HIV- or FIV-infected cells as well as other biological activity related to binding of ligands to chemokine receptors that mediate a number of mammalian embryonic developmental processes.
Claims3
A method to treat atherosclerosis comprising administering 1,1′-[1,4-phenylenebis(methylene)]-bis,1,4,8,11-tetra-azacyclotetradecane, or a salt form thereof, to a subject in need of such treatment a compound of the formula.
Dependencies are inferred from the claim text.