Back to results
US 2006/0069111 A1Published application
Compounds and methods for promoting smoking cessation
AssigneeResearch Triangle Insitute
InventorF. Carroll
Life of this patent
Estimating the term…
Abstract
Compounds and methods for promoting smoking cessation. The compounds may be used to treat a variety of other conditions and disease states.
Claims58
1-71. (canceled)
A method of treating at least one condition selected from the group consisting of smoking addiction, Parkinson's disease, pain, depression, Tourette's syndrome, inflammatory bowel syndrome, schizophrenia, anxiety, epilepsy, attention-deficit hyperactivity disorder, ulcerative colitis and obesity, comprising administering to a patient in need thereof an effective amount of a compound represented by formula (II):
- wherein
- A3 is —R, —N(R)2, —C(═NR)N(R)2, or —OR;
- each Q is, independently, C—X or N, with the proviso that at least one Q is N and at least one Q is C—X;
- each X is, independently, H, halogen, alkyl, alkenyl, alkynyl, aryl, aralkyl, —OH, —OR, —CH2—CO2R, —CO—R, —CO2R, —N(R)2, —NR—CO—R, —CO—N(R)2, —NRCO2R, —SO3CF3, —NO2, —N3, —CF3, —CH═CHY, or —CN, with the proviso that at least one X is represented by the formula:
- each S is, independently, halogen, alkyl, alkenyl, alkynyl, phenyl, aralkyl, —OH, —OR, —CH2—CO2R, —CO—R, —CO2R, —N(R)2, —NR—CO—R, —CO—N(R)2, —NRCO2R, —SO3CF3, —NO2, —N3, —CF3, —CH═CHY, or —CN, or two S, taken together with the phenyl group to which they are bonded, form a 2-naphthyl group;
- c is 1, 2, 3, 4 or 5;
- Y is a halogen;
- and
- each R is, independently, H, alkyl, alkenyl, alkynyl, aryl, or aralkyl;
- or a pharmaceutically acceptable salt thereof.
7 more elements
Dependencies are inferred from the claim text.