Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity

A compound of the formula:

• in which:
• Z is selected from:
• H;
• saturated or unsaturated, straight or branched alkyl, consisting of from 1 to 7 carbon atoms, optionally substituted with alkoxy and halogens;
• aryl or heteroaryl, mono- or bicyclic, containing one or more heteroatoms selected from nitrogen, oxygen and sulphur, optionally substituted with halogens, NO2, OH, alkyls and alkoxy, optionally substituted with halogens;
• arylalkyl or heteroarylalkyl, where the saturated or unsaturated alkyl residue consists of from 1 to 7 carbon atoms, mono- or bicyclic, containing one or more heteroatoms selected from nitrogen, oxygen and sulphur, optionally substituted with halogens, NO2, OH, carboxy, alkyls and alkoxy, optionally substituted with halogens;
• or, together with W, may form a cycle, optionally containing one or more heteroatoms;
• W is equal to H or, together with Z, may form a cycle, optionally containing one or more heteroatoms;
• n=0-10;
• Q is selected from the Z groups listed above;
• X and Y are the same or different and are selected from the Z groups listed above;
• X may be a substituted amino-imino of the formula:
• where Z1 is selected from the Z groups listed above;
• or X is an R—CO group and, with nitrogen, may form a group:
• where R is selected from the Z groups listed above or —OZ or —NZ;
• when n=0, the X—N—Y group is replaced by an H;
• and their pharmacologically acceptable salts, the racemic mixtures, the single enantiomers, stereoisomers and geometric isomers and tautomers,
• with the proviso that the formula (I) compound is not N-(4-aminobutyl)-N′-(γ,γ-dimethylallyl)guanidine methane sulphonate (ST2369) or N-(γ,γ-dimethylallyl)guanidine methane sulphonate (ST 2527).