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US 2006/0069095 A1Published application
Azole derivatives
OwnerThomas Hofmeister, Ulrike Reiff +2inventors
InventorsThomas Hofmeister, Ulrike Reiff, Thomas von Hirschheydt, Edgar Voss
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Abstract
Compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, are disclosed. Also disclosed are methods of preparation of the above-mentioned compounds, pharmaceutical compositions and salts and esters thereof containing them, as well as the use of the above-mentioned compounds in the treatment, control or prevention of illnesses such as cancer.
Claims19
A compound of formula I
- wherein
- R1 is halogenated alkyl;
- R2 is hydrogen or halogen;
- R3 is hydrogen, alkyl or halogen;
- R4 is hydrogen or alkyl;
- said alkyl being optionally substituted one or two times by —OH, —P(O)(alkyl)2, —C(O)OH, —C(O)O-alkyl, —CN, morpholino, —S(O)-alkyl or —S(O)2-alkyl;
- V is —O— or —S—;
- X is carbon or nitrogen;
- and a
- pharmaceutically acceptable salt thereof:
7 more elements
A pharmaceutical composition comprising one or more compounds of formula I together with a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.