Stable amorphous cefdinir
OwnerNancy Sever, Devalina Lawinventors
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Abstract
The present invention relates to stable amorphous 7-[2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamide]-3-vinyl-3-cephem-4-carboxylic acid (syn isomer), methods for its preparation, and pharmaceutical compositions comprising stable amorphous 7-[2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamide]-3-vinyl-3-cephem-4-carboxylic acid (syn isomer).
Claims10
Stable amorphous 7-[2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido]-3-vinyl-3-cephem-4-carboxylic acid (syn isomer).
A pharmaceutical composition comprising stable amorphous 7-[2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido]-3-vinyl-3-cephem-4-carboxylic acid (syn isomer).
A process for producing stable amorphous cefdinir comprising combining cefdinir monohydrate in a methanolic solution and evaporating the solution.
A process for producing stable amorphous cefdinir comprising combining cefdinir monohydrate in an organic solvent in which the solubility of cefdinir monohydrtae isw greater than 0.5 mg/ml and evaoporating the solution.
Dependencies are inferred from the claim text.