Modified glycosaminoglycans, pharmaceutical compositions and methods for oral delivery thereof
OwnerSigmund Lasker, Biswajit Lahiriinventors
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Abstract
This invention provides a composition comprising a depolymerized glycosaminoglycan or derivative thereof covalently linked to a bile acid. This invention also provides a pharmaceutical composition comprising a depolymerized glycosaminoglycan or derivative thereof covalently linked to a bile acid and a pharmaceutically acceptable carrier. Finally, this invention provides a method for orally delivering heparin to a subject comprising administering to the subject a pharmaceutically effective amount of a pharmaceutical composition comprising a glycosaminoglycan or derivative thereof covalently linked to a bile acid and (b) a pharmaceutically acceptable carrier.
Claims16
A composition comprising a depolymerized glycosaminoglycan or derivative thereof covalently linked to a bile acid.
A pharmaceutical composition comprising a composition comprising a depolymerized glycosaminoglycan or derivative thereof covalently linked to a bile acid and a pharmaceutically acceptable carrier.
A method for orally delivering glycosaminoglycan to a subject comprising administering to the subject an anti-coagulating treatment comprising administering to a subject in need thereof an effective anticoagulating amount of a depolymerized glycosaminoglycan or derivative thereof covalently linked to a bile acid and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.