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US 2006/0069039 A1Published application
Treatment of dyskinesia
OwnerAlan Crossman, Michael Hill +2inventors
InventorsAlan Crossman, Michael Hill, Jonathan Brotchie, Montague Silverdale
Life of this patent
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Abstract
The present invention relates to the treatment of dyskinesia with compounds of General Formula (I) such as topiramate. The compound may be topiramate or a derivative thereof. The dyskinesia may be associated with a basil ganglia-related movement disorder such as parkinsonism and may also arise as a side-effect of other therapeutic agents (e.g. L-DOPA).
Claims14
1-13. (canceled)
A method of treating dyskinesia in a subject comprising administering to the subject a therapeutically effective amount of a compound of the formula (I):
- wherein X is Oxygen or CH2;
- R2, R3, R4 and R5 are independently Hydrogen, lower alkyl and R2 and R3 and/or R4 and R5 together may be a group of the formula (II):
- wherein R6 and R7 are the same or different and are Hydrogen, lower alkyl or are alkyl and are joined to form a cyclopentyl or cyclohexyl ring.
Dependencies are inferred from the claim text.