Human kinases
AssigneeIncyte Corporation
InventorsJunming Yang, Mariah Baughn, Neil Burford, Janice Au-Young, Dyung Lu, Roopa Reddy, Henry Yue, Monique Yao, Preeti Lal, Farrah Khan
Life of this patent
Estimating the term…
Abstract
The invention provides human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
Claims28
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of:
- a) an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1-5 and 7-12,
- b) a naturally occurring amino acid sequence having at least 90% sequence identity to an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1-5 and 7-12,
- c) a biologically active fragment of an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1-5 and 7-12, and
- d) an immunogenic fragment of an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1-5 and 7-12.
An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of:
- a) a polynucleotide sequence selected from the group consisting of SEQ ID NO:
- 13-17 and 19-24,
- b) a naturally occurring polynucleotide sequence having at least 90% sequence identity to a polynucleotide sequence selected from the group consisting of SEQ ID NO:
- 13-17 and 19-24,
- c) a polynucleotide sequence complementary to a),
- d) a polynucleotide sequence complementary to b), and
- e) an RNA equivalent of a)-d).
Dependencies are inferred from the claim text.