LEPROTL1 and OB-RGRP genes for screening compounds that act on the gain or loss of weight or on diabetes in a human or animal subject
AssigneeCentre National de la Recherche Scientifique-CNRS, an organization of France
InventorsBernard Bailleul, Yves Rouille, Karin Seron, Sandrine Belouzard
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Abstract
A method for identifying compounds acting on weight gain or weight loss or on diabetes in a human or animal subject including measuring effect of the compounds on (a) expression of at least one of genes LEPROTL1 and OB-RGRP or a part of them and/or (b) intracellular transport up to a cellular membrane and/or (c) presence at the cellular membrane level and/or (d) internalization from the membrane of proteins coded by at least one of these genes or part of them.
Claims19
A method for identifying compounds acting on weight gain or weight loss or on diabetes in a human or animal subject comprising:
- measuring effect of the compounds on (a) expression of at least one of genes LEPROTL1 and OB-RGRP or a part of them and/or (b) intracellular transport up to a cellular membrane and/or (c) presence at the cellular membrane level and/or (d) internalization from the membrane of proteins coded by at least one of these genes or part of them.
Dependencies are inferred from the claim text.