Mononucleotide repeats microsatellite markers for detecting microsatellite instability
AssigneeInstitut National de la Sante et de la Recherche Medicale
InventorsRichard Hamelin, Nirosha Suraweera
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Abstract
A method for evaluating microsatellite instability associated with a tumor, which entails the steps of amplifying microsatellite loci in a biological sample containing genomic DNA from the tumor and determining sizes of DNA amplification products, wherein at least one microsatellite locus selected from the group consisting of NR 21, NR 22, NR 24 and NR 27, is amplified.
Claims22
1-14. (canceled)
A method for evaluating microsatellite instability associated with a tumor, which comprises the steps of:
- a) amplifying microsatellite loci in a biological sample comprising genomic DNA from said tumor;
- and
- b) determining sizes of the DNA amplification products, wherein at least one microsatellite locus selected from the group consisting of NR21, NR22, NR24 and NR27, is amplified.
A pair of primers for amplifying a microsatellite locus selected from the group consisting of NR21, NR22, NR24 and NR27.
Dependencies are inferred from the claim text.