Pharmaceutical formulation
AssigneeGW Pharma Limited
InventorBrian Whittle
Life of this patent
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Abstract
The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.
Claims19
A liquid pharmaceutical formulation, for use in the administration of a lipophilic medicament via a mucosal surface, comprising:
- at least one lipophilic medicament, a solvent and co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulations the formulation is absent of a self emulsifying agent and/or a fluorinated propellant and the formulation has a water content of less than 5%.
A liquid pharmaceutical formulation comprising in a 1 ml vol:
- tetrahydrocannabinol (THC) 27 mg/ml (based on amount of cannabinoid in a botanical drug substance), cannabidiol (CBD) 25 mg/ml (based on amount of cannabinoid in a botanical drug substance), propylene glycol 0.5 ml/ml, peppermint oil 0,0005 ml/ml, and ethanol (anhydrous) gs to 1 ml.
19-79. (canceled)
Dependencies are inferred from the claim text.