Solid dosage form comprising a fibrate and a statin
OwnerPer Holm, Tomas Norlinginventors
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Abstract
The present invention relates to pharmaceutical compositions in particulate form or in solid dosage forms comprising a combination of a fibrate, notably fenofibrate, and a statin (also known as a HMG CoA reductase inhibitors), which compositions are manufactured without any need of addition of water or an aqueous medium and wherein at least 80% of the active substances (i.e. the fibrate and the statin) are present in the composition in dissolved form in order to ensure suitable bioavailability of both active ingredients upon oral administration
Claims91
a particulate material comprising as an active substances one or more fibrates and one or more statins or a pharmaceutically active salt thereof, wherein at least 80% w/w of the total amount of active substances is dissolved in vehicle selected from the group consisting of a hydrophobic, a hydrophilic and a water-miscible vehicles:
38-42. (canceled)
(canceled)
Dependencies are inferred from the claim text.