Class of surfactant-like materials
AssigneeBoehringer Ingelheim Pharmaceuticals, Inc.
InventorsJinjiang Li, Shirlynn Chen, George Gereg, Mariotte Corson
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Abstract
This invention generally refers to a novel class of surfactant-like material that promotes the solubility of poorly soluble compounds.
Claims34
A surfactant-like material comprising Vitamin E TPGS and at least one water soluble polymer and optionally additional carrier or excipients.
A surfactant-like material prepared by the process comprising the steps of:
- (a) dissolving Vitamin E TPGS and a water soluble polymer in a solvent system;
- and
- (b) employing drying technology till the resultant material is a free-flowing powder.
A composition that comprises the surfactant-like material which is a homogenous, amorphous or semi-crystalline powder comprising Vitamin E TPGS and at least one water soluble polymer and a poorly soluble active agent or a tautomer, prodrug, solvate or salt thereof and optionally a pharmaceutically acceptable carriers or excipients.
A surfactant-like material consisting essentially of Vitamin E TPGS and at lease one water soluble polymer and optionally additional carriers or excipients.
Dependencies are inferred from the claim text.