Drug delivery coating for use with a stent
AssigneeAtrium Medical Corporation
InventorsRoger Labrecque, Geoffrey Moodie, Joseph Ferraro, Lisa Rogers, Paul Martakos, Theodore Karwoski, Steve Herweck
Life of this patent
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Abstract
A coated medical device an a method of providing a coating on an implantable medical device result in a medical device having a bio-absorbable coating. The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component can also be provided. The coated medical device is implantable in a patient to effect controlled delivery of the coating, including the therapeutic agent, to the patient.
Claims94
A coated medical device, comprising:
- a coating having a bio-absorbable carrier component, the bio-absorbable carrier component being at least partially formed of a cellular uptake inhibitor and a cellular uptake enhancer, and the coating further including a therapeutic agent;
- wherein the coated medical device is implantable in a patient to effect controlled delivery of the therapeutic agent to the patient;
- and
- wherein the controlled delivery is at least partially characterized by total and relative amounts of the cellular uptake inhibitor and cellular uptake enhancer in the bio-absorbable carrier component.
A method of making a coated medical device, the method comprising:
- providing the medical device;
- and
- applying a coating having a bio-absorbable carrier component, the bio-absorbable carrier component being at least partially formed of a cellular uptake inhibitor and a cellular uptake enhancer, and the coating further including a therapeutic agent;
- wherein the coated medical device is implantable in a patient to effect controlled delivery of the therapeutic agent to the patient;
- and
- wherein the controlled delivery is at least partially characterized by total and relative amounts of the cellular uptake inhibitor and cellular uptake enhancer in the bio-absorbable carrier component.
A coated medical device, comprising:
- a pre-treatment provided on the medical device having a first bio-absorbable carrier component;
- and
- a coating disposed on top of the pre-treatment, the coating having a second bio-absorbable carrier component at least partially formed of a cellular uptake inhibitor and a cellular uptake enhancer, the coating further including a therapeutic agent;
- wherein the pre-treatment improves consistency and conformability and enhances the adhesion of the coating comprising the second bio-absorbable carrier component;
- and
- wherein the coated medical device is implantable in a patient to effect controlled delivery of the therapeutic agent to the patient;
- and
- wherein the controlled delivery is at least partially characterized by total and relative amounts of the cellular uptake inhibitor and cellular uptake enhancer in the bio-absorbable carrier component.
Dependencies are inferred from the claim text.