Immunization with porphyromonas gingivalis protects against heart disease
OwnerCaroline Genco, Frank Gibsoninventors
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Abstract
The invention is directed to a method of preventing and treating a patient having a risk factor and/or a symptom of cardiovascular disease using an immunogenic composition comprising an immunogenically effective portion of Porphyromonas gingivalis in a pharmaceutically effective carrier substance, and a vaccine for same.
Claims12
A method of therapeutically treating a patient having a symptom of cardiovascular disease, said method comprising the steps of:
- (a) providing a patient having a symptom of cardiovascular disease;
- and
- (b) administering to said patient a therapeutic amount of an immunogenic composition comprising an immunogenically effective portion of Porphyromonas gingivalis in a pharmaceutically effective carrier substance.
A method of prophylactically treating a patient having a risk factor for cardiovascular disease, said method comprising the steps of:
- (a) providing a patient having a risk factor for cardiovascular disease;
- and
- (b) administering to said patient a prophylactic amount of an immunogenic composition comprising an immunogenically effective portion of Porphyromonas gingivalis in a pharmaceutically effective carrier substance.
A vaccine against cardiovascular disease comprising a therapeutically effective quantity of an immunogenically effective portion of heat-killed Porphyromonas gingivalis.
Dependencies are inferred from the claim text.