Receptor for lysophosphatidylcholine in vascular endothelial cells and use thereof
OwnerHazel Luminventor
Life of this patent
Estimating the term…
Abstract
A paratope-containing molecule that specifically binds to human GPR4 is disclosed. That molecule preferably specifically binds to an epitope present in the C-terminal 40 residues of human GPR4. Methods of using the paratope-containing molecules and a kit containing the same are also disclosed.
Claims19
A paratope-containing molecule that specifically binds to human GPR4.
A paratope-containing molecule that specifically binds to an epitope present in the C-terminal 40 residues of human GPR4.
A method for assaying for the presence of human GPR4 in a body sample that comprises the steps of:
- (a) contacting a body sample to be assayed with paratope-containing molecules that specifically bind to human GPR4;
- (b) maintaining that contact for a time period sufficient for human GPR4 present in the sample to specifically bind to paratope-containing molecules to form an immunocomplex;
- and
- (c) determining the presence of a formed immunocomplex and thereby the presence of GPR4.
A diagnostic system in kit form useful for assaying for the presence of GPR4 that includes, in a package,
- (a) paratope-containing molecules that immunoreact with GPR4 and utilize an indicating means that signals the presence of an immunocomplex formed between GPR4 and the paratope-containing molecules.
Dependencies are inferred from the claim text.