Initiators and crosslinkable polymeric materials
AssigneeA Enterprises, Inc.
InventorsArthur Ashman, V. Shastri
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Abstract
The present invention relates to novel initiator systems, methods of use, and cured composition for dental, orthopedic and drug delivery purpose. Specifically, it relates to a crosslinkable prepolymer where crosslinking is initiated by a two part system and a composition comprising an admixture of a resorbable bone substitute and a crosslinkable prepolymer. It also relates to the composition formed by crosslinking the admixture and a delivery system for cross-linking the polymer.
Claims30
A initiator system for anhydride polymerization comprising:
- (i) an initiator comprising:
- a light radical generating component,
- a chemical radical generating component, and
- a solvent,
- (ii) an amine accelerator comprising:
- a light accelerator component,
- a chemical accelerator component, and
- a solvent,
- wherein the polymer initiator system is used to initiate polymerization of a crosslinkable anhydride prepolymer.
A curable polymer composition comprising:
- (i) an initiator comprising:
- a chemical radical generating component, and
- an optional light radical generating component;
- (ii) an amine accelerator comprising:
- a chemical accelerator component, and
- an optional light accelerator component, and
- (iii) a curable crosslinkable prepolymer comprising:
- (a) an anhydride of a monomer or oligomer of a diacid or multifunctional acid and a carboxylic acid molecule which includes a crosslinkable group, wherein the crosslinkable group is an unsaturated hydrocarbon moiety;
- or
- (b) a linear polymer selected from the group consisting of linear, hydrophobic biodegradable polymers and linear non-degradable hydrophilic polymers;
- and at least one monomer or macromer containing at least one free radical polymerizable group, wherein at least one of the monomers or macromers includes an anhydride linkage and a polymerizable group selected from the group consisting of acrylate or methacrylate;
- and
- (iv) an optional filler.
A method of forming a polymer comprising:
- (i) mixing
- an initiator comprising a chemical radical generating component, and an optional light radical generating component;
- an amine accelerator comprising a chemical accelerator component, and an optional light accelerator component;
- and
- a curable crosslinkable prepolymer comprising:
- (a) an anhydride of a monomer or oligomer of a diacid or multifunctional acid and a carboxylic acid molecule which includes a crosslinkable group, wherein the crosslinkable group is an unsaturated hydrocarbon moiety;
- or
- (b) a linear polymer selected from the group consisting of linear, hydrophobic biodegradable polymers and linear non-degradable hydrophilic polymers;
- and at least one monomer or macromer containing at least one free radical polymerizable group, wherein at least one of the monomers or macromers includes an anhydride linkage and a polymerizable group selected from the group consisting of acrylate or methacrylate;
- and
- to form an initiated polymer,
- (iii) placing the initiated polymer into a final location, and
- (iv) optionally shining light on the initiated polymer.
Dependencies are inferred from the claim text.