Control of a biological function

A formulation for in situ release in an animal including at least one active component as herein defined for affecting a biological function associated with reproductive processes, in combination with at least one facilitating transfer agent as herein defined, and optionally one or more excipients;

• said facilitating transfer agent including a cyclodextrin, including a suitable cyclodextrin derivative displaying the preferred properties, a solvent.

A formulation for in situ release in an animal including at least one active component as herein defined for affecting a biological function, in combination with at least one facilitating transfer agent as herein defined, and optionally one or more excipients;

• said formulation compatible with at least a second formulation consisting of at least one active component as herein defined for affecting a biological function or any stage of a process thereof, in combination with at least one facilitating transfer agent as herein defined, and optionally one or more excipients, for co-administration or co-delivery within the same administration regime duration at the same site;
• the two formulations being directed to achieve the desired outcome.

A method for affecting a biological function consisting of automated release of active components, the method including an administration regime consisting of at least a first delivery phase for the release of at least a first active component, as well as a second delivery phase for release of at least a second active component, each phase consisting of parameters including one or more of release time, duration, magnitude;

• the release quantity versus time profiles on said two delivery phases differing, and wherein said first and second active components co-operate to achieved a desired outcome.

A method for affecting a biological function consisting of automated release of active components administered in preferred doses via the vaginal route to ensure effective transmucosal absorption of the active required to obtain preferred levels of the active in blood serum for preferred periods.

A method for controlling a biological function by the concurrent operation of multiple delivery phases each directed to the release of a formulation including at least one active, the delivery being in situ and at substantially the same site, and delivered autonomously from a single arrangement in which one or more of the following parameters of release time, duration, magnitude is controlled in said regime.

An animal whose biological function or a stage thereof is being controlled through use of delivery device means.