Use of convertase inhibitors in the treatment of fibrosis and scarring
AssigneeRenovo Limited
InventorsMark William Ferguson, Georg Brunner
Life of this patent
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Abstract
The present invention relates to use of convertase inhibitors for the reduction of scarring during the healing of wounds and also for reducing fibrosis in the treatment of fibrotic conditions.
Claims17
A method for reducing scarring during the healing of wounds, reducing fibrosis in the treatment of fibrotic conditions, or for preventing or inhibiting scar formation or fibrosis, comprising applying a furin inhibitor to a site of a wound or fibrotic disorder or to a site where a wound may form or fibrosis may occur.
The method defined in claim 15 for treating wounds to inhibit or prevent scar formation.
A composition comprising an effective amount of a furin inhibitor for reducing scarring during the healing of wounds, reducing fibrosis in the treatment of fibrotic conditions, or for preventing scar formation or fibrosis, and a pharmaceutically acceptable carrier.
A method of inhibiting the generation of TGF-β1 comprising applying a furin inhibitor to a site where TGF-β1 is generated.
A composition comprising a TGF-β1 generation inhibiting effective amount of a furin inhibitor and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.