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US 2006/0052304 A1Published application
Method for remodeling bone and related sutures
AssigneeBAS Medical, Inc.
InventorDennis Stewart
Life of this patent
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Abstract
The invention relates to the discovery that relaxin receptors exist in bone and related sutures. As such, bone can be remodeled, repaired, removed or grown. Particularly, the invention pertains to a method for modifying a target bone by administering a relaxin compound which binds to relaxin receptors and by monitoring a change in the target bone. The invention further encompasses methods of modifying the height of a human subject.
Claims23
A method for modifying a target bone in a mammalian subject, said method comprising:
- (i) administering a relaxin compound to said subject wherein said compound binds to a relaxin receptor in the target bone;
- and
- (ii) monitoring a change in the target bone, wherein said change results in a modified target bone selected from the group consisting of remodeled bone, repaired bone, bone grown in size and bone grown in length.
A method for modifying height in a human subject, said method comprising:
- (i) administering a relaxin compound to said human subject wherein said compound binds to a relaxin receptor in a target bone;
- and
- (ii) monitoring said subject for a change in said height, wherein said target bone is selected from the group consisting of long bones of the limbs, skeletal bones and vertebral bones.
Dependencies are inferred from the claim text.