US 2006/0051779 A1 · Secreted and transmembrane polypeptides and nucleic acids encoding the same

Abstract

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Claims7

Dependent claims

A method for the diagnosis of neoplastic disease comprising:

(a) identifying a patient suspected of having neoplastic disease;
and
(b) detecting expression of a gene encoding PRO1926 in a test sample from said patient,
wherein lower expression of the gene encoding PRO1926 in said test sample as compared to a normal control sample indicates the presence of neoplastic disease.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

11/103,195Filed 11 Apr 2005

Priority

9 Dec 1999

Published

9 Mar 2006

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07K 14/47
From vertebrates: from mammals
C12Q 1/6886
For diseases caused by alterations of genetic material: for cancer
C12Q 2600/136
Oligonucleotides characterized by their use: screening for pharmacological compounds
C12Q 2600/158
Oligonucleotides characterized by their use: expression markers

Family

Application60/170,262Us provisional application · filed 9 Dec 1999

Application10/006,867Continuation · filed 6 Dec 2001

Application10/063,743Continuation · filed 9 May 2002

Application11/103,195Continuation · filed 11 Apr 2005

US 2002/0119130 A1Published application

US 2003/0180862 A1Published application

US 7,160,985 B2Related patent

US 7,300,758 B2Related patent

US 2006/0051779 A1This patent

From the US filing history. Foreign family members aren’t listed.

Secreted and transmembrane polypeptides and nucleic acids encoding the same

Life of this patent

Secreted and transmembrane polypeptides and nucleic acids encoding the same

Life of this patent

Abstract

Claims7