Microprojection array with improved skin adhesion and compliance
OwnerJames Matriano, Michel Cormier +1inventors
InventorsJames Matriano, Michel Cormier, Peter Daddona
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Abstract
A transdermal delivery system having a microprojection array with one or more voids configured to allow an adhesive backing to attach to a user's skin and, hence, improve retention of the system thereto. Radial voids can be configured to enhance compliance of the array to conform more readily to non-flat areas of the skin.
Claims28
A device for transdermally delivering a pharmacologically active agent, the device comprising:
- a member having a plurality of stratum corneum-piercing microprojections;
- at least one active agent adapted to be delivered transdermally by the microprojections;
- and
- at least one void in the member that allows an adhesive backing to communicate through the void.
A device for transdermally delivering a pharmacologically active agent, the device comprising:
- a member having a plurality of stratum corneum-piercing microprojections;
- at least one active agent coated on at least one of the microprojections;
- at least one void in the member;
- and
- an adhesive backing that allows the adhesive backing to communicate with a subject through the at least one void enabling increased uniformity of adhesion across the member.
A method of transdermally delivering a pharmacologically active agent, the method comprising:
- providing a delivery system having a microprojection member that includes a plurality of stratum corneum-piercing microprojections, at least one active agent adapted to be delivered transdermally by the microprotrusions, an adhesive backing, and at least one void in the member to allow the adhesive backing to communicate through the void;
- and
- applying the member to a surface so that the adhesive backing communicates with the surface through the void.
Dependencies are inferred from the claim text.