Vessel isolation device

A vessel isolation system, comprising

• a noninflatable expandable body, reversibly expandable from a low profile collapsed state to a generally hourglass-shaped expanded state, including
• a proximal portion having at least one inlet formed therein,
• a distal portion having at least one outlet formed therein, the outlet being in fluid communication with the inlet, and
• a neck portion disposed between the proximal and distal portions;
• a blood impermeable sleeve disposed about the neck portion of the expandable body and at least a portion of the proximal and distal portions of the expandable body, the sleeve being reversibly expandable with the expandable body from the collapsed state to the expanded state,
• wherein the sleeve is placed in apposition to a vessel wall adjacent to the proximal portion and the distal portion when the expandable body is in the expanded state, creating an isolated treatment space;
• and
• means for deploying the expandable body from the collapsed state to the expanded state.

A method of treating a vessel comprising:

• providing a noninflatable, expanding vessel isolation device;
• locating the vessel isolation device at a treatment site in a collapsed state such that a proximal portion of the vessel isolation device is proximal of the treatment site and a distal portion of the vessel isolation device is distal of the treatment site;
• expanding the vessel isolation device from a collapsed state to an expanded state;
• applying a treatment to the vessel;
• collapsing the vessel isolation device from the expanded state to the collapsed state;
• and
• removing the vessel isolation device from the vessel.