Synergistic conjugated linoleic acid (CLA) and carnitine combination

A method of treating a secondary condition of obesity in an obese patient wherein said secondary condition is selected from the group consisting of diabetes mellitus type I and II, high glucose levels, hyperlipidemia, hypercholesterolemia, metabolic syndrome X, kidney failure and high blood pressure in a patient or subject comprising coadministering to said patient or subject a synergistic effective amount of a combination of a compound according to the chemical structure:

• where R is H or a C2 to C20 straight or branch-chained alkanoyl group, or a pharmaceutically acceptable salt thereof in combination with conjugated linoleic acid.

A composition comprising a mixture of at least 100 mg of a compound according to the chemical structure:

• where R is H or a C2 to C20 straight or branch-chained alkanoyl group, or a pharmaceutically acceptable salt thereof in combination with at least 250 mg of conjugated linoleic acid, optionally in combination with a pharmaceutically acceptable carrier, additive or excipient.

A method of treating obesity in a patient in need thereof, comprising administering to said patient a synergistic effective amount of a combination of carnitine or a pharmaceutically acceptable salt or derivative thereof and conjugated linoleic acid wherein said method results in said patient losing at least about 1% body weight within a period of less than about six months.

A method of treating obesity in a patient in need thereof, comprising administering to said patient a synergistic effective amount of a combination of carnitine or a pharmaceutically acceptable salt or derivative thereof and conjugated linoleic acid wherein said method results in the body mass index of said patient decreasing by at least about 0.5% within a period of less than about six months.