Composition and method for the treatment of psoriasis
OwnerJohan Stjernschantz, Bahram Resulinventors
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Abstract
The use of a prostaglandin A2 derivative, and prodrugs of the compound, for the manufacture of a medicament for the treatment and/or alleviation of psoriasis is presented, as well as a method of treatment, involving the topical application of such prostaglandins. Compositions containing a therapeutically active, and physiologically acceptable amount of the above compound or derivatives thereof, as such or in the form of a prodrug, in a suitable vehicle are also described. Importantly, the derivatives can be applied in therapeutically active amounts without or with only minimal side effects, such as hyperemia, irritation or pain.
Claims11
1-5. (canceled)
A composition for topical application, said composition containing a therapeutically active and physiologically acceptable amount of 17-phenyl-18,19,20-trinor-PGA2 or a derivative thereof for the treatment and/or alleviation of psoriasis.
A method for the treatment and/or alleviation of psoriasis in a human patient, wherein a therapeutically active and physiologically acceptable amount of a prostaglandin is applied topically to a psoriatic lesion on the skin of said patient, wherein said prostaglandin is 17-phenyl-18,19,20-trinor-PGA2 or a derivative or prodrug thereof.
Dependencies are inferred from the claim text.