Back to results
US 2006/0040958 A1Published application
Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
AssigneeSchering Corporation
InventorsTimothy Guzi, Kamil Paruch, Michael Dwyer
Life of this patent
Estimating the term…
Abstract
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
Claims24
A compound of the formula:
- wherein R18 is an alkyl or heterocyclyl with said heterocyclyl being linked to the isothiazole ring shown in the formula above via a carbon atom on said heterocyclyl,
- or a pharmaceutically acceptable salt, solvate, ester or prodrug of said compound.
A compound of formula:
- or a pharmaceutically acceptable salt, solvate, ester or prodrug of said compound.
Dependencies are inferred from the claim text.