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US 2006/0040949 A1Published application
Novel compounds with antibacterial activity
AssigneeMorphochem AG
InventorsJean Surivet, Cornelia Zumbrunn, Christian Hubschwerlen, Annabelle Honer
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Abstract
The present invention describes novel anti-bacterial compounds of formula (I).
Claims13
Compounds of formula (I):
- wherein
- A is an oxygen, sulphur or nitrogen atom or a C1-4alkylene, C2-4alkenylene, C2-4alkynylene or C1-4heteroalkylene group,
- X1, X2, X3, X4 and X5 are each independently of the others nitrogen atoms or groups of formula CR2,
- R1 is a hydrogen atom, a halogen atom, a hydroxy group, an alkyloxy group or a heteroalkyloxy group,
- R2 is a hydrogen atom, a halogen atom, or a hydroxy, alkyl, alkenyl, alkynyl or heteroalkyl group,
- R3 is selected from the following groups:
- the radicals R4, each independently of any other(s), are a hydroxy group, a C1-6alkyl group or a C1-8heteroalkyl group,
- R5 is an alkyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl, cycloalkyl, alkylcycloalkyl, heteroalkyl-cycloalkyl, heterocycloalkyl, aralkyl or heteroaralkyl radical,
- n is 0, 1, 2 or 3 and
- m is 0 or 2,
- or a pharmacologically acceptable salt, solvate, hydrate or a pharmacologically acceptable formulation thereof.
8 more elements
Dependencies are inferred from the claim text.