Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of renal colic

A method of treating renal colic in a patient the method comprising administering to said patient a therapeutically effective amount of a carbinol compound of formula (II)

• wherein
• R31 represents a hydrogen atom, a linear or branched alkyl radical, a linear or branched alkenyl radical, an optionally at least mono-substituted cycloaliphatic radical optionally having at least one nitrogen atom as a ring member, or a phenyl radical,
• R32 represents a hydrogen atom, a cycloaliphatic radical having a least one nitrogen atom as a ring member and optionally substituted with at least one radical independently selected from the group consisting of linear or branched alkyl radical optionally bound via a linear or branched alkylene group, —NR33R34, bound via linear or branched alkylene group, and —NR35R36 bound via a linear or branched alkylene group,
• R33 and R34 independently represent a linear or branched alkyl radical or an unsubstituted benzyl radical,
• R35 and R36 together with the nitrogen atom to which they are bonded represent a saturated, unsubstituted heterocyclic radical optionally having at least one further heteroatom as a ring member,
• X represents a phenyl radical or a thienyl radical, wherein said phenyl radical or said thienyl radical is optionally substituted with at least one substituent independently selected from the group consisting of a linear or branched alkyl radical, a linear or branched alkoxy group, a linear or branched alkyl radical, which is at least partially halogenated and a halogen atom,
• Y represents a heteroaryl radical, which contains one or more nitrogen atoms as ring members and which is unsubstituted or at least mono-substituted by one or more substituent independently from one another selected from the group consisting of a halogen atom, a linear or branched alkyl radical, a benzyl radical, a cyano group bound via a linear or branched C1-4-alkylene group, a carboxy group bound via a linear or branched C1-4-alkylene group, a methoxy carbonyl group bound via a linear or branched C1-4-alkylene group, a hydroxy group bound via a linear or branched C1-4-alkylene group, an amino group bound via a linear or branched C1-4-alkylene group, a (C1-4) dialkylamino group bound via a linear or branched C1-4-alkylene group, and a cycloaliphatic radical, which contains at least one nitrogen atom as ring member and which is bound via a linear or branched C1-4-alkylene group, or Y represents an unsubstituted heteroaryl radical, which contains two nitrogen atoms as ring members and which is condensed with a saturated, one methyl-substituted nitrogen atom as ring member containing cycloaliphatic group, or a stereoisomer, enantiomer diastereomer, or racemate thereof or a mixture of at least two stereoisomers enantiomers or diastereomers thereof or a corresponding salt or solvate thereof.