Rotating seals for cell processing systems

A treated cell population comprising:

• a population of hematopoetic cells having enzymatically converted blood serotypes, the hematopoetic cells enzymatically converted by using a cell processing system comprising,
• i. a supply module having a fluid distribution module and a plurality of supply containers;
• ii. a cell module;
• iii. a processing module including one or more fluid containers connected to the fluid distribution module by a set of conduits, the containers having a flexible chamber comprising a first side and a second side, each side having a circumferential integral annular seal extending into the container lumen;
• iv. a control module;
• v. a plurality of conduits connecting the supply module to the processing module, and the cell module to the processing module;
• vi. a plurality of valves all adapted to the control module and individually adapted to either the supply module, the cell module or the processing module, the operation of the valves being regulatable by the control module;
• and
• vii. a plurality of sensors all adapted to the control module and individually adapted to either the supply module, the processing module or the cell module, the cell module sensor comprising a weight sensor;
• wherein the system is environmentally closed and provides for sterile enzymatic conversion of the hematopoetic cells.