Back to results
US 2006/0040258 A1Published application
Water-soluble conjugates and methods of preparation
OwnerHuiyan Guo, Lorraine Bautista +2inventors
InventorsHuiyan Guo, Lorraine Bautista, Zurong Wu, Jinn-nan Lin
Life of this patent
Estimating the term…
Abstract
The present invention provides water-soluble conjugates and methods of using them in diagnostic and detection assays. Devices for performing detection and quantitation assays are also provided. In various embodiments the conjugates are useful in immunoassays and later flow assays. The invention also provides methods of preparing the conjugates that result in higher yields and higher sensitivities for the assays.
Claims20
1-60. (canceled)
A method for preparing a water-soluble conjugate, comprising:
- simultaneously reacting a water-soluble intermediate precursor comprising a carrier and a linker with a targeting element for a ligand to be detected or a ligand to be detected, and a non-specific protein;
- forming a suspension containing a precipitate of the water-soluble conjugate;
- and
- extracting the water-soluble conjugate from the suspension.
1 more element
Dependencies are inferred from the claim text.