Intranasal delivery of antipsychotic drugs
OwnerDaniel Wermeling, Jodi Millerinventors
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Abstract
An intranasal drug product is provided including an antipsychotic drug, such as haloperidol, in sprayable solution in an intranasal metered dose sprayer. Also provided is a method of administering an antipsychotic drug, such as haloperidol, to a patient, including the step of delivering an effective amount of the antipsychotic drug to a patient intranasally using an intranasal metered dose sprayer. A method of treating a psychotic episode also is provided, the method including the step of delivering an antipsychotic drug, such as haloperidol, intranasally in an amount effective to control the psychotic episode.
Claims55
A device for delivering an antipsychotic drug intranasally, comprising an intranasal metered dose sprayer containing one or more doses of a sprayable solution comprising an amount of an antipsychotic drug effective to treat a psychotic episode.
A method of treating a psychotic episode, comprising the step of delivering intranasally an amount of an antipsychotic drug effective to treat the psychotic episode in a sprayable solution.
A method of administering an antipsychotic drug to a patient, comprising the step of delivering intranasally an amount of an antipsychotic drug effective to treat a psychotic episode in a sprayable solution.
A sprayable solution for use in an intranasal metered dose sprayer, comprising
- a) from greater than 0.25% wt. to about 10% wt. haloperidol or a dose equivalent thereof of an antipsychotic drug other than haloperidol;
- and
- b) a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.