Pharmaceutical compositions and methods for the prevention of drug misuse
OwnerDavid Preston, James Newman +1inventors
InventorsDavid Preston, James Newman, Matthew Heck
Life of this patent
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Abstract
A pharmaceutical composition including a therapeutic does of an active ingredient susceptible of either intentional or accidental misuse by over-utilization and a sub-therapeutic dose of a compound in an amount sufficient to elicit an undesirable response if the recommended therapeutic dose of the active ingredient is exceeded. A multiple dose pharmaceutical dosage form including an effective amount of an active ingredient for a patient in need of treatment thereof and a urine indicator capable of changing the color of the patient's urine when a desired dosage of the active ingredient is exceeded by ingestion of multiple doses in excess of a desired treatment regimen.
Claims23
A multiple dose pharmaceutical dosage form comprising an effective amount of an active ingredient for a patient in need of treatment thereof and a urine indicator capable of changing the color of the patient's urine when a desired dosage of the active ingredient is exceeded by ingestion of multiple doses in excess of a desired treatment regimen.
A method for indicating when a patient ingesting multiple doses of a pharmaceutical dosage form exceeds a desired treatment regimen comprising:
- a. observing the color of a patient's urine;
- b. ingesting one or more doses of a pharmaceutical dosage form including an effective amount of an active ingredient for a patient in need of treatment thereof and a urine color shift indicator capable of changing the color of the patient's urine when a desired dosage of the active ingredient is exceeded by ingestion of multiple doses in excess of a desired treatment regimen;
- c. observing the color of a patient's urine after ingesting one or more of the doses;
- d. comparing the color of the patent's urine before and after ingesting one or more of the doses to determine if there is a substantial change in color of the patient's urine.
Dependencies are inferred from the claim text.