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AssigneeClemson University
InventorsRichard Marcus, Rayman Stanelle
Estimating the term…
Monolithic cartridges including a plurality of nominally aligned polymer fibers can be used as stationary phase materials for liquid chromatography separations. Bundles of fibers are packed together so as to form capillary channels between the fibers. Different polymer compositions permit the “chemical tuning” of the separation process. The fibers can be physically or chemically bonded at spaced locations throughout the cartridge or can be packed together under pressure by use of an encasing wrap to form the capillary channels. Use of fibers allows a wide range of liquid flow rates with very low backpressures. Applications in HPLC, cap-LC, prep-scale separations, analytical separations, waste remediation/immobilization, extraction of selected organic molecules/ions from solution, purification of liquid streams (process waste, drinking water, pure solvents), selective extraction of cell matter and bacteria from growth media, and immobilization of cell matter and bacteria are envisioned.
A separation device comprising a monolithic cartridge comprising a plurality of nominally aligned polymeric fibers and a nonporous wrap surrounding the plurality of fibers and disposed along the axial length of the aligned fibers, wherein at least a portion of the fibers are bonded to one another, the monolithic cartridge defining a plurality of capillaries capable of wicking a fluid between adjacent fibers.
A separation device comprising a monolithic cartridge comprising a plurality of nominally aligned polymeric fibers and a nonporous wrap surrounding the plurality of fibers and disposed along the axial length of the aligned fibers, the nonporous wrap exerting radial pressure upon the fibers such that the monolithic cartridge defines a plurality of capillaries capable of wicking a fluid between adjacent fibers.
A separation device comprising
A method comprising:
A method comprising:
Dependencies are inferred from the claim text.