Composition and method for the repair and regeneration of cartilage and other tissues

A method for repair and/or regeneration in cartilaginous tissue comprising administering at a site of the cartilaginous tissue in need of repair an effective amount of a polymer composition comprising:

• a polymer;
• and
• blood,
• wherein the polymer is selected from the group consisting of polylactic acid, polyglycolic acid, a synthetic homo and block copolymers containing carboxylic, amino, sulfonic, phosphonic, phosphenic functionalities with or without additional functionalities, and further
• wherein when the polymer is combined with blood the polymer composition is converted into a non-liquid state in time or upon heating such that the polymer composition when placed at the site in need of repair the polymer composition will adhere to the site in need of repair to effect reconstruction or bulking of the tissue and/or regeneration thereof.

A method for repair and/or regeneration in cartilaginous tissue comprising administering at a site of the cartilaginous tissue in need of repair an effective amount of a thermogelling composition comprising:

• chitosan;
• glycerol phosphate;
• and
• blood,
• wherein the thermogelling composition is converted into a non-liquid state in time or upon heating, said composition once converted into a non-liquid state adheres to the site in need of repair when placed thereon to effect reconstruction or bulking of the tissue and/or regeneration thereof.