Scorpion peptide as hypotensive agent

An isolated or synthetic peptide expressed in a venom of a scorpion, wherein the peptide comprises at least two features selected from the group consisting of:

• i) lack of Cystein residues and lack of internal disulfide bridges;
• ii) a molecular signature at a C-terminal ending or portion, described as:
• Xaa-Pro-Pro or Xaa-Pro-Pro-Ala, where Xaa is any amino acid residue;
• iii) pairs of amino acid residues effective to form a protective shield against amino-, endo- and carboxi-proteinases enzymes;
• and iv) Hypotensive effects in vertebrates.

An isolated or synthetic peptide complete, partial or modified sequences of a member selected from the group consisting of SEQ ID NO:

• 1;
• SEQ ID NO:
• 2;
• SEQ ID NO:
• 3 and SEQ ID NO:
• 4, wherein the peptide is an anti-hypertensive agent.