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US 2005/0241024 A1Published application
Transgenic plant-based vaccines
OwnerWilliam Langridge, Jie Yu +1inventors
InventorsWilliam Langridge, Jie Yu, Takeshi Arakawa
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Abstract
A DNA construct that encodes, when expressed in a plant cell, a protein complex comprising five monomeric fusion proteins; where each fusion protein comprises a cholera toxin B subunit linked at the 3′ end of the cholera toxin B subunit to a first immunogenic antigen from a causal factor of a first infectious mammalian disease other than cholera; and where the antigen elicits a protective response to the disease.
Claims12
A DNA construct that encodes, when expressed in a plant cell, a protein complex comprising five monomeric fusion proteins;
- where each fusion protein comprises a cholera toxin B subunit linked at the 3′ end of the cholera toxin B subunit to a immunogenic antigen from a causal factor of a infectious mammalian disease other than cholera;
- and
- where the antigen elicits a protective response to the disease.
Dependencies are inferred from the claim text.