Pharmaceutical composition that is used to control blood glucose in patients with type 2 diabetes
AssigneeSilanes S.A. de C.V.
InventorJose Manuel Francisco Ochoa
Life of this patent
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Abstract
Pharmaceutical compositions of the active substances glimepiride with metformin or its salts such as hydrochloride, succinate, furmarate, etc. are useful to control blood glucose in patients with type 2 diabetes. To prove the effectiveness of the combination, clinical studies were conducted that demonstrated the existence of not only an additive effect, but also a synergistic effect of the two drugs compared with monotherapy using only one of the drugs used in combination. In consequence, the combination may be used as an effective and safe therapy to control blood glucose in patients with type 2 diabetes, using different proportions of the active substances in combinations suitable for the needs of different patients.
Claims11
A pharmaceutical composition comprising glimepiride and metformin or a pharmaceutically acceptable salts in amounts and weight ratio sufficient to provide a synergistic control of blood glucose levels in a patient with type 2 diabetes.
A method of controlling blood glucose levels in a patient with type 2 diabetes, comprising administering to said patient to synergistic combination of glimepiride and a pharmaceutically acceptable salt of metformin.
Dependencies are inferred from the claim text.