Methods for treating and preventing hypertension and hypertension-related disorders
OwnerStephanie Watts, Carrie Northcottinventors
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Abstract
The present invention provides methods for treating hypertension and conditions associated with hypertension utilizing compounds that selectively inhibit PI-3-K p110δ activity.
Claims37
A method of ameliorating or preventing hypertension or a condition associated with hypertension, comprising administering to an individual an amount of a phosphoinositide 3-kinase delta (PI-3-Kδ) selective inhibitor effective to ameliorate or prevent hypertension or a condition associated with hypertension and inhibit vascular p110 delta (p110δ).
A method of treating hypertension or a condition associated with hypertension, comprising:
- identifying a subject with hypertension or a condition associated with hypertension;
- and
- administering to the subject an amount of a phosphoinositide 3-kinase delta (PI3Kδ) selective inhibitor effective to treat the hypertension or the condition associated with hypertension,
- thereby treating hypertension or a condition associated with hypertension in the subject.
A method of ameliorating or preventing hypertension or a condition associated with hypertension, comprising administering to an individual an amount of a phosphoinositide 3-kinase delta (PI-3-Kδ) selective inhibitor having the structure
- in an amount effective to ameliorate or prevent hypertension, or a condition associated with hypertension, and inhibit vascular p110 delta (p110δ).
A method of treating hypertension or a condition associated with hypertension, comprising:
- identifying a subject with hypertension or a condition associated with hypertension;
- and
- administering to the subject an amount of a phosphoinositide 3-kinase delta (PI-3-Kδ) selective inhibitor having the structure
- in an amount effective to ameliorate or prevent hypertension, or a condition associated with hypertension, and inhibit vascular p110 delta (p110δ),
- thereby treating hypertension or a condition associated with hypertension in the subject.
Dependencies are inferred from the claim text.