Tissue volume reduction
AssigneeAeris Therapeutics, Inc.
InventorEdward Ingenito
Life of this patent
Estimating the term…
Abstract
Devices, compositions, and methods for achieving non-surgical lung volume reduction (e.g., bronchoscopic lung volume reduction (BLVR)) are described. BLVR can be carried out by collapsing a region of the lung, adhering one portion of the collapsed region to another, and promoting fibrosis in or around the adherent tissue.
Claims18
A method for reducing lung volume in a patient, the method comprising introducing a material into a target region of a lung;
- and collapsing the target region to reduce the volume of the lung, wherein the material comprises an anti-surfactant, or an adhesive, or a combination thereof.
A method for reducing air flow into and out of a region of a lung, the method comprising introducing a material into a target region of a lung.
A method of preparing a diseased region of a lung for volume reduction, the method comprising introducing a material into a diseased region of a lung, wherein the material is introduced via a bronchoscope, and wherein the material comprises an anti-surfactant, an adhesive, another biocompatible reagent, or a combination of two or more thereof.
A method for promoting stable lung collapse, the method comprising introducing a material into a target region of a lung and blocking air flow into and out of the target region under conditions to promote collapse and/or fibrosis or scarring of the target region.
A method of treating emphysema, the method comprising introducing a material into a target region of a lung under conditions to promote collapse and/or fibrosis or scarring within the target region, wherein the material is introduced non-surgically.
A method of inducing stable lung volume reduction, the method comprising collapsing a lung region under conditions to promote fibrosis or scarring in the collapsed region.
Dependencies are inferred from the claim text.