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US 2005/0239198 A1Published application
Stirred-tank reactor system
AssigneesBaxter International Inc., Baxter Healthcare S.A.
InventorsKurt Kunas, Robert Oakley
Life of this patent
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Abstract
The present invention relates to a stirred-tank reactor system and methods of preparing such systems. The present invention further encompasses the use of the stirred-tank reactor system as a disposable bioreactor and in kits with disposable elements.
Claims42
A stirred-tank reactor system, comprising:
- (i) a flexible bag with at least one opening, wherein the bag functions as a sterile container for a fluidic medium;
- (ii) a shaft situated within the bag;
- (iii) an impeller attachable to said shaft, wherein said impeller is used to agitate the fluidic medium to provide a hydrodynamic environment;
- and
- (iv) a bearing attached to said shaft and to said opening of the bag.
2 more elements
A method for preparing a stirred-tank reactor system, comprising:
- (i) providing a flexible bag with at least one opening, wherein the bag functions as a sterile container for a fluidic medium;
- (ii) inserting a shaft with an impeller attachable to said shaft into the bag, wherein said impeller is used to agitate the fluidic medium to provide a hydrodynamic environment;
- (iii) attaching a bearing to said shaft and to said opening of the bag;
- and
- (iv) sealing the bag to the shaft and the bearing such that the inside of the bag remains sterile.
2 more elements
Dependencies are inferred from the claim text.