Modulation of STAT 6 expression
AssigneeIsis Pharmaceuticals, Inc.
InventorsWilliam Shanahan, Susan Freier, Kenneth Dobie
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Abstract
Compounds, compositions and methods are provided for modulating the expression of STAT 6. The compositions comprise oligonucleotides, targeted to nucleic acid encoding STAT 6. Methods of using these compounds for modulation of STAT 6 expression and for diagnosis and treatment of disease associated with expression of STAT 6 are provided.
Claims15
A compound 8 to 80 nucleobases in length targeted to a nucleic acid molecule encoding STAT 6, wherein said compound specifically hybridizes with at least an 8 nucleobase portion of nucleobases 146 to 177 of said nucleic acid molecule encoding STAT 6 (SEQ ID NO:
- 4) and inhibits the expression of STAT 6.
10-13. (canceled)
18-24. (canceled)
Dependencies are inferred from the claim text.